产品货号：
Z28798
中文名称：
Trefoil Factor 1/TFF1抗体
英文名称：
Anti-Trefoil Factor 1/TFF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Trefoil Factor 1/TFF1 Antibody |
| 指标别名 | D21S21;HP1.A;HPS2;pNR 2;Polypeptide P1.A;Protein pS2;pS2;TFF1;trefoil factor 1 |
| 克隆性 | Polyclonal |
| 检验物种 | rat |
| 应用范围 | WB,IHC |
| 基因名称 | TFF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of mouse Estrogen Inducible Protein pS2(59-72aa CCFDDSVRGFPWCF),identical to the related rat sequence. |
| 实际分子量 | 12KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TFF1(Trefoil factor 1),also known as pS2,is a protein that in humans is encoded by the TFF1 gene.Members of the trefoil family are characterized by having at least one copy of the trefoil motif,a 40-amino acid domain that contains three conserved disulfides.They are stable secretory proteins expressed in gastrointestinal mucosa.Their functions are not defined,but they may protect the mucosa from insults,stabilize the mucus layer,and affect healing of the epithelium.It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals.Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin,and inhibition was dose dependent and inhibited by TFF1 antisera,particularly by antisera directed to the TFF1 C terminus.Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls.This gene,which is expressed in the gastric mucosa,has also been studied because of its expression in human tumors.This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. |
| Uniprot ID | Q08423 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | trefoil factor 1 |
| 蛋白名全称 | Trefoil factor 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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